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Risks of NSAIDs You Should Know

Nonsteroidal anti-inflammatory drugs (NSAIDs) include over-the-counter drugs like Ibuprofen (Motrin, Advil) and aspirin. A paper published in The American Journal of Accountable Care noted the frequent and serious complications that are all too typical for those who regularly use these drugs:


  • “A systematic review of 17 prospective observational studies found that 11% of preventable drug-related hospital admissions could be attributed to NSAIDs.”
  • “Studies have documented that the risk of adverse events associated with NSAIDs are both dose-dependent and duration dependent”
  • myocardial infarction (MI), stroke, kidney problems, and gastrointestinal (GI) bleeding as some of the serious potential side effects
  • “Some estimates suggest that each year more than 100,000 patients are hospitalized for NSAID-related GI complications alone”
  • “NSAID use has been associated with increased risk for hospitalization due to MI as well as for heart failure (HF).”
  • “Likewise, acute renal failure, which is also associated with NSAID use, can ultimately lead to expensive dialysis treatment.”


Just because a drug is sold without a prescription, doesn’t mean it doesn’t have serious side effects.

Read the Paper

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